Haemolytic Disease of the Newborn*
نویسنده
چکیده
Since the discovery of the Rh blood groups (Landsteiner and Weiner, 1940) many articles on the subject of haemolytic disease of the newborn have been written. Gilmour (1944) in this country and Potter (1944; 1946) in America have presented authoritative accounts of the pathology of haemolytic disease, but, as the former points out, this aspect of the condition has received far less attention than it has merited.
منابع مشابه
A case of severe haemolytic disease of the newborn due to anti-Di(a) antibody.
Red cell allo-antibodies directed against the Diego (Di) blood group antigen have rarely been reported to cause a haemolytic reaction against transfusion or haemolytic disease of the newborn. The frequency of the Di(a+) phenotype among the Hong Kong Chinese population is estimated to be 4.4%. We report on a case of severe haemolytic disease of the newborn due to anti-Di(a) antibody--the first l...
متن کاملLiver Function Tests in Survivors of Haemolytic Disease of the Newborn.
Hepatocellular damage is sometimes a feature of severe haemolytic disease during the newborn period and might be expected to lead to permanent liver damage in some cases. Gerrard (1952), however, in a study of 226 cases of icterus gravis neonatorum, followed for more than five years, found little support for this hypothesis. His investigations included clinical examination, thymol turbidity tes...
متن کاملNecrotizing enterocolitis in a newborn following intravenous immunoglobulin treatment for haemolytic disease.
ABO iso-immunization is the most frequent haemolytic disease of the newborn. Treatment depends on the total serum bilirubin level, which may increase very rapidly in the first 48 hours of life in cases of haemolytic disease of the newborn. Phototherapy and, in severe cases, exchange transfusion are used to prevent hyperbilirubinaemic encephalopathy. Intravenous immunoglobulins (IVIG) are used t...
متن کاملHaemolytic disease of the newborn due to multiple maternal antibodies
Haemolytic disease of the foetus and newborn (HDFN) is a condition in which the lifespan of an infant’s red blood cells (RBCs) is shortened by the action of specific maternal immunoglobulin G (IgG) antibody. Rhesus (Rh)D haemolytic disease of the newborn is a prototype of maternal isoimmunization and foetal haemolytic disease. Although rare, the other blood group antigens capable of causing all...
متن کاملIncidence of haemolytic disease of the newborn in the offspring of sisters.
Haemolytic disease of the newborn most commonly occurs when an Rh-negative mother has been sensitized to the D antigen, either from an Rh-positive foetus during pregnancy, or by an injection or transfusion of blood. Sensitization, however, occurs much less commonly than is theoretically possible; and Wiener (1946) has suggested that the ability of an individual to become sensitized is condition...
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